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1-10 of 21 results for pyroglutamate amyloid-β

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Research article

First published 2014

Identification of N-Terminally Truncated Pyroglutamate Amyloid-β in Cholesterol-Enriched Diet-Fed Rabbit and AD Brain

Roxanna Perez-Garmendia, Luis Fernando Hernandez-Zimbron, Miguel Angel Morales [...]

Journal of Alzheimer’s Disease

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Research article

First published 2014

Brain Pyroglutamate Amyloid-β is Produced by Cathepsin B and is Reduced by the Cysteine Protease Inhibitor E64d,Representing a Potential Alzheimer's Disease Therapeutic

Gregory Hook, Jin Yu, Thomas Toneff [...]

Journal of Alzheimer’s Disease

Open access

Research article

First published 2018

Comprehensive Characterization of the Pyroglutamate Amyloid-β Induced Motor Neurodegenerative Phenotype of TBA2.1 Mice

Tina Dunkelmann, Sarah Schemmert, Dominik Honold [...]

Journal of Alzheimer’s Disease

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Research article

First published 2015

Neuron Loss and Behavioral Deficits in the TBA42 Mouse Model Expressing N-Truncated Pyroglutamate Amyloid-β 3–42

Julius N. Meißner, Yvonne Bouter, Thomas A. Bayer

Journal of Alzheimer’s Disease

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Research article

First published 2015

I716F AβPP Mutation Associates with the Deposition of Oligomeric Pyroglutamate Amyloid-β and α-Synucleinopathy with Lewy Bodies

Evelyn Sieczkowski, Ivan Milenkovic, Vivek Venkataramani [...]

Journal of Alzheimer’s Disease

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Research article

First published 2013

Oligomeric Pyroglutamate Amyloid-β is Present in Microglia and a Subfraction of Vessels in Patients with Alzheimer's Disease: Implications for Immunotherapy

Oliver Wirths, Antje Hillmann, Laurent Pradier [...]

Journal of Alzheimer’s Disease

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Research article

First published 2012

Detection of Peri-Synaptic Amyloid-β Pyroglutamate Aggregates in Early Stages of Alzheimer's Disease and in AβPP Transgenic Mice Using a Novel Monoclonal Antibody

Markus Mandler, Edward Rockenstein, Kiren Ubhi [...]

Journal of Alzheimer’s Disease

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Research article

First published 2018

Generation and Partial Characterization of Rabbit Monoclonal Antibody to Pyroglutamate Amyloid-β 3-42 (pE 3 -Aβ)

Pankaj D. Mehta, Bruce A. Patrick, Marc Barshatzky [...]

Journal of Alzheimer’s Disease

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Review article

First published 2015

Inhibition of Glutaminyl Cyclase Ameliorates Amyloid Pathology in an Animal Model of Alzheimer's Disease via the Modulation of γ-Secretase Activity

Hyundong Song, Yu Jin Chang, Minho Moon [...]

Journal of Alzheimer’s Disease

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Research article

First published 2012

Antibody 9D5 Recognizes Oligomeric Pyroglutamate Amyloid-β in a Fraction of Amyloid-β Deposits in Alzheimer's Disease without Cross-Reactivity with other Protein Aggregates

Vivek Venkataramani, Oliver Wirths, Herbert Budka [...]

Journal of Alzheimer’s Disease

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