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Research article

First published 2018-12

Clinical pharmacokinetics,pharmacodynamics,safety,and tolerability of JNJ-54175446,a brain permeable P2X7 antagonist,in a randomised single-ascending dose study in healthy participants

Maarten Timmers, Paulien Ravenstijn, Liwen Xi [...]

Journal of Psychopharmacology

Open access

Research article

First published 2020-4

Safety,tolerability,and pharmacokinetics of the selective prostacyclin receptor agonist ralinepag in single and multiple dosing studies of an immediate-release oral formulation in healthy volunteers

John S. Grundy, Christopher D. King, John W. Adams [...]

Pulmonary Circulation

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Research article

First published 1997-6

Safety,Tolerability,and Pharmacokinetics of Sumatriptan in Healthy Subjects Following Ascending Single Intranasal Doses and Multiple Intranasal Doses

KHP Moore, EK Hussey, S Shaw [...]

Cephalalgia

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Research article

First published 2024-10

A Phase 1 single ascending dose study of pure oral harmine in healthy volunteers

Jessica L Ables, Leah Israel, Olivia Wood [...]

Journal of Psychopharmacology

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Research article

First published 2018-2

Safety and pharmacodynamics of venetoclax (ABT-199) in a randomized single and multiple ascending dose study in women with systemic lupus erythematosus

P Lu, R Fleischmann, C Curtis [...]

Lupus

Open access

Research article

First published 2017-12

A double-blind,placebo-controlled,single ascending-dose study of remyelinating antibody rHIgM22 in people with multiple sclerosis

Andrew Eisen, Benjamin M Greenberg, James D Bowen [...]

Multiple Sclerosis Journal – Experimental,Translational and Clinical

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Research article

First published 2016-12

Pharmacokinetics and Tolerability of Single-Ascending Doses of Desvenlafaxine Administered to Children and Adolescents with Major Depressive Disorder

Robert L. Findling, James Groark, Karen A. Tourian [...]

Journal of Child and Adolescent Psychopharmacology

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Research article

First published 2021-1

Pharmacokinetics,safety and tolerability of single- and multiple-ascending doses of JNJ-64530440,a novel hepatitis B virus capsid assembly modulator,in healthy volunteers

Thomas N Kakuda, Jeysen Z Yogaratnam, Christopher Westland [...]

Antiviral Therapy

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Research article

First published 2003-4

A Single Ascending Dose Study of Epigallocatechin Gallate in Healthy Volunteers

U Ullmann, J Haller, JP Decourt [...]

Journal of International Medical Research

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Research article

First published 2024

First-In-Human Safety,Tolerability,and Pharmacokinetics of Single and Multiple Doses of AZP2006,A Synthetic Compound for the Treatment of Alzheimer’s Disease and Related Diseases

Philippe Verwaerde, Cecilia Estrella, Stéphane Burlet [...]

Journal of Alzheimer’s Disease

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