Antidotal therapy is useful for only a meager number of poisonous agents in which reversal of the effects of the toxin, or treatment of the toxin-induced pathophysiologic derangements, is possible. This review of selected antidotes is meant to acquaint the reader with some of the new and/or controversial uses for a few of our older agents, to introduce two new agents recently marketed, and to refresh information on antidotes not often used.
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