This peer-reviewed journal focuses exclusively on the medicinal value and biomedical effects of food materials. International in scope, the journal advances the knowledge of the development of new foods and dietary supplements targeted at promoting health-span and the prevention and treatment of disease. Primary areas of interest include: effects of foods, bioactive food constituents and supplements on metabolic outcomes and disease risk, prevention and/or treatment; impact of food bioactives on aging, health-span, and lifespan; modulation of nutrigenomic, metabolomic and other -omic-based indicators of disease outcome modification; and safety & toxicology of food bioactives and dietary supplements. The journal welcomes bioactive and supplement studies in validated model systems and/or clinical outcomes. Studies describing the identification, purification, or characterization of novel bioactives must be accompanied by a demonstration of a significant biological outcome in a relevant system (in vitro or in vivo is acceptable) to be considered for publication.