Abstract
Herpes zoster oticus produces facial paralysis with a low recovery rate. Acyclovir, a specific virostatic drug, was given intravenously in five herpes zoster oticus patients, and in three of them was followed by oral therapy. In follow-ups of 1 to 24 months, one patient had grade I recovery, three patients grade II, and one grade III. These good results encourage the use of acyclovir in herpes zoster oticus patients.
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References
1.
Crabtree
JA
. Herpes zoster oticus . Laryngoscope 1968 ; 78 : 1853 –78 .
2.
Mair
IWS
Flugsrud
LB
. Peripheral palsy and herpes zoster infection . J Laryngol Otol 1976 ; 90 : 373 –9 .
3.
Robillard
RB
Hilsinger
RL
Jr
Adour
KK
. Ramsay Hunt facial paralysis: clinical analyses of 185 patients . Otolaryngol Head Neck Surg 1986 ; 95 : 292 –7 .
4.
Fleury
P
Basset
JM
Compere
JF
. Idiopathic facial paralysis and facial paralysis due to herpes zoster. Follow-up and therapeutic indications [in French] . Rev Laryngol Otol Rhinol (Bord) 1978 ; 99 : 307 –22 .
5.
Taverner
D
. Electrodiagnosis in facial palsy . Arch Otolaryngol 1965 ; 81 : 470 –7 .
6.
Payten
RJ
Dawes
JDK
. Herpes zoster of the head and neck . J Laryngol Otol 1972 ; 86 : 1031 –55 .
7.
Gold
D
Corey
L
. Acyclovir prophylaxis for herpes simplex virus infection . Antimicrob Agents Chemother 1987 ; 31 : 361 –7 .
8.
Dorsky
DI
Crumpacker
CS
. Drugs five years later: acyclovir . Ann Intern Med 1987 ; 107 : 859 –74 .
9.Acyclovir sodium . In: AMA drug evaluations . 6th ed. Chicago, Ill : American Medical Association , 1986 : 1623 –5 .
10.
Stafford
FW
Welch
AR
. The use of acyclovir in Ramsay Hunt syndrome . J Laryngol Otol 1986 ; 100 : 337 –40 .
11.
Dickins
JRE
Smith
JT
Graham
SS
. Herpes zoster oticus: treatment with intravenous acyclovir . Laryngoscope 1988 ; 98 : 776 –9 .
12.
House
JW
Brackmann
DE
. Facial nerve grading system . Otolaryngol Head Neck Surg 1985 ; 93 : 146 –7 .
13.
Kanzaki
J
. Electrodiagnostic findings in the early stages of Bell's palsy and Ramsay-Hunt's syndrome . Acta Otolaryngol [Suppl ] (Stockh ) 1988 (suppl 446 ): 42 –6 .
