Chronic Rhinosinusitis and the Risk of Erectile Dysfunction

Abstract

Chronic rhinosinusitis is a common disease associated with reductions in quality of life across a range of measures, including sexual health. We conducted a case-control study assessing chronic rhinosinusitis prevalence among men with and without clinically significant erectile dysfunction. We found that chronic rhinosinusitis was significantly associated with erectile dysfunction (odds ratio = 2.0, 95% CI = 1.8-2.4, P < .001) and that this association remained significant even when the interval between chronic rhinosinusitis diagnosis and erectile dysfunction treatment was restricted. This study adds to a growing body of literature demonstrating an association between chronic rhinosinusitis and sexual dysfunction.