Tobacco use is the leading preventable cause of morbidity and mortality in the United States. Nicotine replacement therapy (NRT) remains a first-line pharmacotherapy for tobacco and smoking cessation. Five formulations of NRT for delivery of nicotine were approved by the US Food and Drug Administration between 1984 and 2002, including 3 available without prescription from pharmacies. A table was created as a tool for pharmacists to counsel patients about the NRT products. The table summarizes available doses, dosing regimen and schedules, administration technique, contraindications, and adverse effects.