Background: The impact of premature frailty in HIV-infected individuals on the prevalence of sexual behaviors and sexually transmitted infections (STIs) is unknown. Methods: We compared these factors among individuals aged ≥18 years, who had prior determination of a frailty phenotype at the Washington University HIV Clinic between June and December 2008. All P values were 2-tailed and considered significant at <.05. Results: Of 445 individuals (71% male, 30% Caucasian, median age 43 years) assessed, the prevalence of frailty was 9%. Reports of recent sexual activity (44%) did not differ by frailty status. Consistent condom use (69% overall) was similar between sexually active frail and nonfrail individuals, and there was no significant difference in STI prevalence between groups (0 vs 32 [9%], P = .08). Conclusion: In this relatively young population, frailty did not affect reports of recent sexual activity or consistent condom use and no significant difference in STI prevalence was observed.
Desquiblet L. , Jacobson LP, Fried LP, et al., for the Multicenter AIDS Cohort Study. HIV-1 infection is associated with an earlier occurrence of a phenotype related to frailty. J Gerontol. 2007; 62(11):1279-1286.
2.
Desquilbet L. , Margolick JB, Fried LP, et al., for the Multicenter AIDS Cohort Study. Relationship between a frailty-related phenotype and progressive deterioration of the immune system in HIV-infected men. J Acquir Immune Defic Syndr. 2009; 50(3):299-306.
3.
Önen NF , Agbebi A., Shacham E., et al. Frailty among HIV-infected persons in an urban outpatient care setting. J Infect. 2009; [Epub ahead of print].
4.
Fried L., Tangen CM, Waltson J., et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001;56(3): M146-M156.
5.
Desquiblet L. , Margolick JB, Fried LP, et al. Frailty and time from HAART initiation to AIDS or death. XVI International AIDS Conference . 2006; Abstract MOPE0338.
6.
Gorbach PM, Drumright LN, Daar ES, Little SJTransmission behaviors of recently HIV-infected men who have sex with men . J Acquir Immune Defic Syndr. 2006;42(1):80-85.
7.
Weinhardt LS , Carey MPHuman immunodeficiency virus testing and behavior change. Arch Intern Med.1999;159(17): 1994-2000.
8.
Illa L., Brickman A., Saint-Jean G., et al. Sexual risk behaviors in late middle age and older HIV seropositive adults. AIDS Behav. 2008;12(6):935-942.
9.
Önen NF , Shacham E., Stamm KE, Overton ETComparisons of sexual behaviors and new STD diagnoses among older and younger individuals with HIV infection. AIDS Care. In press.
10.
Cooperman NA , Arnsten JH, Klein RSCurrent sexual activity and risky sexual behavior in older men with or at risk for HIV infection. AIDS Educ Prev. 2007;19(4):321-333.
11.
Lovejoy TI, Heckman TG, Sikkema KJ, et al. Patterns and correlates of sexual activity and condom use in behavior in persons 50-plus years of age living with HIV/AIDS. AIDS Behav. 2008;12(6): 943-956.
12.
Dolezal C., Meyer-Bahlburg HF, Liu X., et al. Longitudinal changes in sexual risk behavior among HIV+ and HIV- male injecting drug users. Am J Drug Alcohol Abuse. 1999;25(2): 281-303.
13.
Tun W., Gange SJ, Vlahov D., Strathdee SA, Celentano DDIncrease in sexual risk behavior associated with immunologic response to highly active antiretroviral therapy among HIV-infected injection drug users. Clin Infect Dis. 2004;38(8): 1167-1174.
14.
Shacham E., Basta TB, Reece M.Relationship of psychological distress and unprotected sex among individuals with HIV seeking mental health care. J Int Assoc Physicians AIDS Care.2009;8(2): 93-99.
15.
Pulerwitz J. , Amaro H., De Jong W., Gortmaker SL, Rudd R.Relationship, power, condom use and HIV risk among women in the USA. AIDS Care. 2002;14(6):789-800.
16.
Gomez CA, Van Oss Marin B.Gender, culture and power: barriers to HIV-prevention strategies for women . J Sex Res. 1996; 33(4):355-362.
17.
Needles RF, Dennis G., Weahterby N., et al. Reliability of self-reported HIV risk behaviors of drug users . Psychol Addict Behav. 2005;9(4):242-250.
18.
Clayton A., Ramamurthy S.The impact of physical illness on sexual dysfunction. Adv Psychosom Med. 2008;29:70-88.
19.
Neundorfer M. , Braudy Harris P., Britton PJ, Lynch DAHIV-risk factors for midlife and older women . Gerontologist. 2005;45(5): 617-625.
20.
Gregorian RS , Golden KA, Bahce A., et al. Antidepressant-induced sexual dysfunction . Ann Pharmacother. 2002 ;36(10):1577-1589.
21.
Mota NP, Cox BJ, Katz LY, et al. Relationship between mental disorders/suicidality and three sexual behaviors: results from the National Comorbidity Survey Replication . Arch Sex Behav. 2009; [Epub ahead of print].
22.
Zemishlany Z., Weizman A.The impact of mental illness on sexual dysfunction . Adv Psychosom Med. 2008 ;29:89-106.
23.
Raiford JL, Diclemente RJ, Wingood GMEffects of fear of abuse and possible STI acquisition on the sexual behavior of young AfricanAmerican women. Am J Public Health.2009;99(6): 1067-1071.
24.
Pérez-Jiménez D., Seal DW, Serrano-García I.Barriers and facilitators of HIV prevention with heterosexual Latino couples: beliefs of four stakeholder groups. Cultur Divers Ethnic Minor Psychol. 2009;15(1):11-17.
25.
Tross S., Campbell AN, Cohen LR, et al. Effectiveness of HIV/ STD sexual risk reduction groups for women in substance abuse treatment programs: results of NIDA Clinical Trials Network Trial. J Acquir Immune Defic Syndr. 2008;48(5):581-589.
26.
Holmes L. Jr , Ogungbade GO, Ward DD, et al. Potential markers of female condom use among inner city African-American women. AIDS Care . 2008;20(4):470-477.
27.
Durant LE, Carey MPReliability of retrospective self-reports of sexual and nonsexual health behaviors among women. J Sex Marital Ther. 2002;28(4):331-338.
28.
Shacham E., Cottler LBSexual behaviors: rates and reliability. Arch Sex Behav. in press.
