Sage Journals: Discover world-class research

Abstract

In this article, near infrared spectroscopic measurements of hemoglobin concentration in whole blood, which are potentially useful in a pulse oximeter modified for non-invasive hemoglobinometry, are presented. The best one-, two-, three- and four-filter calibrations are presented. In addition, a calibration is presented that uses absorbance at three wavelengths, 586 nm, 816 nm and 1300 nm because this calibration is employed by a prototypic non-invasive hemoglobinometer which is under development. For a similar calibration, data is presented that show the relative contributions of the absorbance at each wavelength to the overall measurement. The best three-filter calibration occurred in the longer wavelength near infrared region, and used the absorbance at 1626 nm, 1628 nm and 1638 nm. This calibration gave better performance than the calibrations in the shorter wavelength region.

Keywords

hemoglobin concentration near infrared non-invasive hemoglobinometry

Get full access to this article

View all access options for this article.

References

Polish

L.B.

Shapiro

C.N.

Bauer

Klotz

Ginier

Roberto

R.R.

Margolis

H.S.

and Alter

M.J.

, N. Engl. J. Med. 326, 721 (1992).

Maier

J.S.

Barbieri

Chervu

Fantini

Franceschini

M.A.

Levi

Mantulin

W.W.

Rosenberg

Walker

S.A.

and Gratton

, SPIE 2387, 240 (1995).

Patterson

M.S.

Chance

and Wilson

B.C.

, Appl. Opt. 28, 2331 (1989).

Marcu

Maarek

J.M.I.

Bembi

and Howell

, SPIE 2387, 218 (1995).

Kelleher

J.F.

, J. Clin. Monit. 5, 37 (1989).

Kuenstner

J.T.

Norris

K.H.

and McCarthy

W.F.

, Appl. Spectrosc. 48, 484 (1994).

Kuenstner

J.T.

, United States Patent 5,377,674, “Method For Non-Invasive and In-Vitro Hemoglobin Concentration Measurement,” filed May 8, 1992 and issued January 3, 1995.

Henry

J.B.

(Ed.), Clinical Diagnosis & Management by Laboratory Methods. W.B. Saunders Co., Philadelphia, PA, pp. 1368 and 1371 (1991).

Zijlstra

W.G.

Buurmsa

and der Roest

Meeuwsenvan W.P.

, Clin. Chem. 37(9), 1633 (1991).

10.

Wray

Cope

Delpy

D.T.

Wyatt

J.S.

and Reynolds

E.O.R.

, Biochim. Biophys. Acta. 933, 184 (1988).

11.

Kuenstner

J.T.

and Norris

K.H.

, J. Near Infrared Spectrosc. 2, 59 (1994).

12.

Collins

J.R.

, Phys. Rev. 26, 771 (1925).

13.

Steuer

R.R.

and Harris

D.H.

, United States Patent 5,372,136, “System and Method for Noninvasive Hematocrit Monitoring,” filed February 1, 1993 and issued December 13, 1994.

14.

Henry

J.B.

(Ed.), Clinical Diagnosis & Management by Laboratory Methods. W.B. Saunders Co., Philadelphia, PA, pp. 560 and 558 (1991).

15.

Steuer

R.R.

Harris

D.H.

and Conis

J.M.

, Am. Clin. Lab., 18 (June 1992).

16.

Zwart

Buursma

van Kampen

E.J.

Oeseburg

van der Ploeg

P.H.W.

and Zijlstra

W.G.

, J. Clin. Chem. Clin. Biochem. 19, 457 (1981).

17.

Rodak

B.F.

, in Clinical Hematology: Principles, Procedures, Correlations, Ed by Lotspeich-Steininger

C.A.

Stiene-Martin

E.A.

and Koepke

J.A.

J.B. Lippincott Co., Philadelphia, PA, pp. 112–113 (1992).

Near Infrared Hemoglobinometry

Abstract

Keywords

Get full access to this article

References