Abstract
A series of new 6,6-dimethyl-9-oxo-4,5,6,7,8,9-hexahydropyrazolo[5,1-b]quinazoline substituted benzenesulfonohydrazide and 1,3,4-oxadiazole derivatives has been synthesised and characterised using spectral techniques. The antiviral activity of these compounds against an avian paramyxovirus (APMV-1) has been screened and the results show that some of the compounds possess good antiviral activity
Get full access to this article
View all access options for this article.
References
1.
Elie R.
,
Rüther E.
,
Farr I.
,
Emilien G.
, and
Salinas E.
, J. Clin. Psychiatry , 1999 , 60 , 536 .
2.
Baumann M.
,
Baxendale I.R.
, Beil. J. Org. Chem. , 2013 , 9 , 2265 .
3.
Ackermann P.
,
Margot P.
, and
Müller F.
, “Fungicides, Agricultural” , Ullmann's Encyclopedia of Industrial Chemistry. , Electronic Release, Wiley-VCH , Weinheim , 2000
4.
Mark E.B.
,
John P.M.
,
Stephen D.A.S.
, and
Anthony W.
, U.S. Patent: 6670366 B1, issued 30 December 2003 .
5.
Sawant S.D.
,
LakshmaReddy G.
,
Dar M.I.
,
Srinivas M.
,
Gupta G.
,
Sahu P.K.
,
Mahajan P.
,
Nargotra A.
,
Singh S.
,
Sharma S.C.
,
Tikoo M.
,
Singh G.
,
Vishwakarma R.A.
, and
Syed S.H.
, Bioorg. Med. Chem. , 2015 , 23 , 2121 .
6.
Baviskar A.T.
,
Banerjee U.C.
,
Gupta M.
,
Singh R.
,
Kumar S.
,
Gupta M.K.
,
Kumar S.
,
Raut S.K.
,
Khullar M.
,
Singh S.
, and
Kumar R.
, Bioorg. Med. Chem. , 2013 , 8 , 5782 .
7.
Ghofrani H.A.
,
Osterloh I.H.
, and
Grimminger F.
, Nat. Rev. Drug Discov. , 2006 , 5 , 689 .
8.
Anthony M.M.
, and
Roger J.D.
, Nat. Rev. Drug Discov. , 2003 , 2 , 554 .
9.
Sekiya T.
,
Hiranuma H.
,
Uchide M.
,
Hata S.
, and
Yamada S.
, Chem. Pharm. Bull. , 1981 , 29 , 948 .
10.
John R.K.
,
Huaqing L.
,
Irene D.
,
David G.W.
,
Tracy L.C.
,
Arlene M.M.
,
Ivan M.
,
Marina I.S.
,
Thomas R.M.
,
Timothy A.E.
,
Jorge D.B.
, and
Marlon C.
, Biorg. Med. Chem. Lett. , 2010 , 20 , 1900 .
11.
Gilbert B.E.
, and
Knight V.
, Antimicrob. Agents Chemother. , 1986 , 30 , 201
12.
Hebert M.F.
, and
Guglielmo B.J.
, Drug Intell. Clin. Pharm. , 1990 , 8 , 735 .
13.
Fackler J.C.
,
Flannery K.
,
Zipkin M.
, and
McIntosh K.
, J. Med. , 1990 , 9 , 634 .
14.
Sekiya T.
,
Hiranuma H.
,
Uchide M.
,
Hata S.
, and
Yamada S.
, Chem. Pharm. Bull. , 1981 , 29 , 948 .
15.
Randy J.G.
,
Melissa M.S.
,
Katherine S.Y.
, and
Ralph W.
, Bioconjug. Chem. , 2014 , 25 , 2081 .
16.
Gerlier D.
, and
Thomasset N.
, J. Immunol. Methods , 1986 , 94 , 57 .