Human and Experimental Toxicology (HET), an international, peer-reviewed, open access journal, is dedicated to publishing nonclinical and clinical original research papers and in-depth reviews that comprehensively cover functional, biochemical, and structural disorders in toxicology. The principal aim of HET is to publish timely high impact hypothesis driven scholarly work with an international scope. The journal publishes on: Structural, functional, biochemical, and molecular effects of toxic agents Studies that address mechanisms/modes of toxicity Safety evaluation of novel chemical, biotechnologically-derived products, and nanomaterials for human health assessment including statistical and mechanism-based approaches Novel methods or approaches to research on animal and human tissues (medical and veterinary patients) investigating the functional, biochemical, and structural disorder In vitro techniques, particularly those supporting alternative methods Novel approaches exploring e.g. adverse outcome pathways, also in the context of risk assessment of chemicals Papers will be judged based on scientific originality and contribution to the field and quality and subject matter. Papers describing effects on humans or experimental animals only of local interests; it is important that the results can be generalized to wider audiences and applications. Authors must clearly identify chemically the material tested and briefly explain what novel toxic effect (s) or toxic mechanism (s) of the chemical is being reported and what their significance is. HET does not accept case reports and case studies. HET does not accept papers on herbal or other extracts unless sufficient chemical characterization of the material under investigation is supplied. HET does not publish routine toxicological studies without an aim to define novel mechanisms of toxicity. The same applies to studies that utilize excessive doses of chemicals/toxicants without any relevance with the human situation. Open access information From January 2022, HET will become a fully open access journal. All articles that are accepted for publication will be subject to an open access article processing charge (APC) of 3000 USD and will be published with a Creative Commons license. The APC is payable when a manuscript is accepted after peer review, before it is published. The APC is subject to taxes where applicable. Please see further details here . Submit your manuscript today at https://mc.manuscriptcentral.com/het .